Choose an island base

Florida Keys hotels, resorts and lodging

Compare hotels, motels, resorts, inns and guest houses by island so overnight plans work with the activities, driving time and services that matter most.

Plan with confidence

The best base depends on the trip. Key Largo and Islamorada work well for Upper Keys water activities, Marathon shortens many Middle Keys drives, and the Lower Keys or Key West place visitors closer to the southern end of the route.

Before booking, confirm parking, resort fees, room configuration, accessibility, boat-trailer rules and pet restrictions directly with the property. A Keys mailing address does not always describe the most practical island location.

This hub is for hotels, motels, resorts and guest houses—not a catalog of private apartments scraped from a map. For a 5–7 day week, two or three southbound pillows usually beat one hotel for seven nights or a new island every afternoon. Organic directory order is not sold; Featured means stronger verification or a disclosed sponsorship.

How to use this page
  1. Choose the Key before the brand. Upper Keys pillows support dawn boats; Key West pillows support walking and Tortugas check-in.
  2. Open the property source for parking, fees and pet rules. A mailing address is not a marina location.
  3. Plan two or three bases on a longer trip. The where-to-stay-by-Key guide explains the patterns.

Practical questions

Before you trust a listing

Should I book one hotel for the whole week?

Usually no, if the trip spans reef time and Key West. A 5–7 night split-base beats one hotel for seven days or a new island every night.

Why does a Keys address not match the island I meant?

Postal cities and property names often cover several keys. Check the mile marker, oceanside vs bayside, and whether parking or a marina is actually on-site.

Does KeysCompass rank hotels?

No. Organic directory order is not sold. Confirm rates, fees and pet rules with the property. Featured means stronger verification or a disclosed sponsorship, not a purchased slot.

Browse the directory

Hotels & Lodging by island

194 listings with source links.

Refine resultsOptional service and dog-friendly filters

Map-only places stay searchable when you show more map listings.

194 places found · hiding 52 map-only listings

Florida Keys tours, rentals & outfitters scene
KeysCompass categoryTours, Rentals & Outfitters
Verified source

Key Largo · Tours, Rentals & Outfitters

Amoray Dive Center

Scuba & snorkelingBoat toursInstruction

Iconic Key Largo dive resort with dock-departing dive and snorkel packages; lodging is on the same property. FKNMS Blue Star listed as Amoray Dive Center.

104250 Overseas Hwy, Key Largo, FL 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
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Key Largo · Hotels & Lodging

Anchorage Resort & Yacht Club

Waterfront resort and timeshare property in Key Largo with one-bedroom suites that open onto waterfront balconies. Its marina rents boat slips, and guests can fish from the docks.

107800 Overseas Highway, Key Largo

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
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Key Largo · Hotels & Lodging

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Resort on 15 acres of former pineapple plantation along Florida Bay in southern Key Largo, part of Hilton's Curio Collection. It has a beach, pools, a spa, watersports rentals on Coconut Beach and restaurants including Calusa and Dry Rocks, and non-guests can buy day, week or month passes.

97000 Overseas Hwy, Key Largo, FL 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
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Key Largo · Hotels & Lodging

Bay Harbor & Coconut Bay Resort

Bay Harbor Lodge and Coconut Bay Resort are one Key Largo lodging operator at 97702 Overseas Hwy.

97702 Overseas Hwy, Key Largo, FL 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
Verified source

Key Largo · Hotels & Lodging

Bungalows Key Largo

LodgingResorts

Adults-only, all-inclusive resort at 99010 Overseas Highway in Key Largo, built for a relaxing Florida Keys escape for grown-ups.

99010 Overseas Highway, Key Largo, FL 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
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Key Largo · Hotels & Lodging

Courtyard Key Largo

Marriott hotel in Key Largo with an on-site marina of 77 slips for boats up to 60 feet, an outdoor pool and whirlpool, a fitness center and The Bistro for breakfast with Starbucks coffee. Dogs up to 30 pounds are allowed for a fee, and on-site parking is free.

99751 Overseas Highway, Key Largo, FL 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
Verified source

Key Largo · Hotels & Lodging

Gilbert's Resort

LodgingHotels

Key Largo hotel lodging at 107900 Overseas Hwy. The Tiki Bar at Gilbert's Resort is a separate restaurant listing.

107900 Overseas Hwy, Key Largo, FL 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
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Key Largo · Hotels & Lodging

Hampton Inn Key Largo

Dog-friendly

Hampton by Hilton hotel on Overseas Highway in Key Largo with free hot breakfast, an outdoor pool, a fitness center and a beach, plus free parking and Wi-Fi. Check-in is 3 p.m. and check-out is 11 a.m.

102400 Overseas Highway, Key Largo, FL 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
Open data

Key Largo · Hotels & Lodging

Key Largo Inn

No pets reported

Caribbean-style motor lodge in central Key Largo, established in 1952 and renovated over the years, within walking distance of restaurants. It has a swimming pool, a full bar, a scuba dive shop and an adjacent wine bar, with free breakfast items and internet; smoking and pets are not allowed.

99202 Overseas Highway, Key Largo, FL 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
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Key Largo · Hotels & Lodging

Key Lime Sailing Club and Cottages

Bayside cottage resort in Key Largo with self-contained waterfront cottages. Stays include unlimited use of the club's sailboats, kayaks, canoes, paddleboards, snorkel gear, bicycles and fishing gear, plus a tiki hut and barbecue grills, and sailing lessons are offered.

99306 Overseas Highway, Key Largo, FL 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
Verified source

Key Largo · Hotels & Lodging

Kona Kai Resort, Gallery & Botanic Gardens

LodgingResorts

Key Largo resort lodging at 97802 Overseas Hwy, with a gallery and botanic gardens on the property.

97802 Overseas Hwy, Key Largo, FL 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
Verified source

Key Largo · Hotels & Lodging

Largo Resort

LodgingResorts

Independent boutique resort on six private acres on Florida Bay in Key Largo, with a 300-foot private beach. Separate from Playa Largo.

101740 Overseas Hwy, Key Largo, FL 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
Verified source

Key Largo · Hotels & Lodging

Marina Del Mar Resort And Marina

Marina Del Mar Resort And Marina is a Key Largo lodging at 527 Caribbean Drive and also lists a 77-slip marina. The operator marina page says slips can take boats up to 60 feet with up to a 20-foot beam, with water, cable and electric service at slips, and an on-site boat ramp that has restrictions. The marina is described as a jet-ski free zone.

527 Caribbean Drive, Key Largo, FL, 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
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Key Largo · Hotels & Lodging

Mariner's Club Key Largo

Mariner's Club Key Largo is a lodging option in Key Largo, Florida Keys. The mapped name and location come from public map contributors; we do not guess phones, hours or ratings.

97501 Overseas Highway, Key Largo, FL, 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
Open data

Key Largo · Hotels & Lodging

Playa Largo Resort & Spa

Autograph Collection resort on 14.5 acres of private shoreline on Florida Bay in Key Largo, with a white-sand beach, calm water for swimming and snorkeling from shore, a spa and restaurants including Sol by the Sea. Evenings bring Eventide, a sunset gathering with live music.

97450 Overseas Hwy, Key Largo, FL 33037

Florida Keys hotels & lodging scene
KeysCompass categoryHotels & Lodging
Open data

Key Largo · Hotels & Lodging

Popp's Motel

Bayfront motel at mile marker 95.5 in Key Largo that Alex and Bertha Popp made their home in 1951, with nine cottages on two acres. There is a 200-foot-wide sandy beach, a shaded picnic area with hammocks, tiki huts and grills, a dock and a shallow 1950s boat ramp for kayaks and paddleboards.

95500 Overseas Hwy, Key Largo, FL 33037